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First detection of the equine herpesvirus 1 neuropathogenic variant in Brazil

Author(s) : E. Mori, et al.

Summary :

This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G2254/D752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A2254/N752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.
 
Keywords
Brazil – DNA polymerase gene – Equine herpesvirus 1 – Neurological disease – Neuropathogenic.

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