Excerpt of product info
|Product title :||
Quantitative human health risk assessments of antimicrobial use in animals and selection of resistance: a review of publicly available reports
|Author(s) :||S.A. McEwen|
Quantitative risk assessments have been conducted to estimate the probability and magnitude of adverse human health effects from antimicrobial use in food animals through selection for antimicrobial resistance in bacteria. The majority focused on licensed antimicrobials under regulatory scrutiny, including growth promoters and agents of critical importance to human health. Most used models to attribute fractions of surveillance-derived estimates of antimicrobial-resistant infections in humans to antimicrobial use in animals. Risk estimates ranged from a few additional illnesses per million at risk, to many thousands. Although useful, published quantitative risk assessments have been unable to comprehensively address important aspects of antimicrobial resistance, including multiple exposure pathways, interrelationships among bacteria, co-selection, and cumulative effects of antimicrobial use in multiple species and countries.
Antibiotic – Antimicrobial agent – Resistance – Risk analysis – Risk assessment – Risk characterisation.